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br Experimental Procedures Human fetal
2018-11-14

Experimental Procedures Human fetal tissues were obtained from Novogenix Laboratories following informed consent and elective termination. Developmental age was determined by ultrasound. Adult articular chondrocytes and synovial membrane were obtained from National Disease Research Interchange. P
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br Materials and methods br Results br
2018-11-14

Materials and methods Results Discussion The effect of donor MSCs in tumor growth remains controversial (Cho et al., 2009). Discrepancies concerned to whether they promote or suppress it may be due to disparities in cell source, isolation and expansion conditions, via and timing of administ
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leukotriene receptor antagonist br Acknowledgements This wor
2018-11-14

Acknowledgements This work was supported by the IRET Foundation (2015-2016), Ozzano Emilia, Italy (no-profit organization), in the frame of the “Step-by-step” POR-FESR 2016-2020 Emilia Romagna Region project. Introduction Resident neural stem cells (NSCs) persist in the adult mammalian centra
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Using Eqs and the expression for
2018-11-14

Using Eqs. (10) and (11), the expression for the matrix telomerase inhibitor of the dipole operator can be represented in the form where Here is the reducible self-energy part of Green\'s function; the integration is once again performed over the whole set of HF states. This, using Eq. (12),
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The gene of the sigma receptor is
2018-11-14

The gene of the sigma-1 receptor is located on chromosome 9p13, known due to its being associated with psychotic disorders [6]. The sigma-1 receptor, with its small size (223 amino-acid residue), binds with medium or high affinity to a wide range of chemical compounds of very different structural cl
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Several limitations in our study need
2018-11-14

Several limitations in our study need to be considered when interpreting its results. As mentioned above, we did not examine social capital as a construct, which is comprised of a wider range of factors than the items that were included in our study. We also are unable assert that fewer social conne
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fty720 br Materials and Methods br Results br Discussion Stu
2018-11-14

Materials and Methods Results Discussion Studies have suggested that dual-tropic strains evolve from R5 variants, and X4 viruses arise from the R5X4 strains (Pastore et al., 2004). It is unlikely that the emergence of a dual-tropic virus during the passage experiments occurred by chance bec
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In addition to classical receptor targets such as EGFR Roove
2018-11-14

In addition to ‘classical’ receptor targets such as EGFR (Roovers et al., 2007,2011; Schmitz et al., 2013; Omidfar et al., 2013), HER2 (Jamnani et al., 2012; Even-Desrumeaux et al., 2012), c-MET (Slordahl et al., 2013) and VEGFR (Behdani et al., 2012), nanobodies against new targets such as the DR5
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br Materials and Methods br Results br Discussion Although g
2018-11-14

Materials and Methods Results Discussion Although genome-wide association studies provide a systematic, powerful, and unbiased method for studying the common disease/common variant (CDCV) hypothesis of complex disorders such as schizophrenia, the identification of susceptibility loci for sc
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A number of animal models
2018-11-14

A number of animal models have been developed for studying the pathogenesis and evaluating countermeasures for ZIKV infection. Rhesus macaques with subcutaneous ZIKV inoculation develop mild clinical signs that resemble the self-limiting illness in most infected immunocompetent adults (Dudley et al.
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br T Cell specific Immunotherapies
2018-11-14

T Cell-specific Immunotherapies Have Proved Ineffective at Blocking Relapsing MS The question remains about the nature of the peripheral target for immunotherapy. There is abundant evidence to suggest that MS is a mainly CD4 Th1/Th17 T-cell mediated disease (Martin et al., 2016). This concept is
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order Cy3.5 hydrazide br propose that the absence of violet
2018-11-14

propose that the absence of “violet” light (VL, near ultraviolet (UV), below 400nm) in our industrialized world is a major contributing factor for the recent epidemic increase in myopia. They conclude from their study that artificial lighting should be revised to include a UV component, as in sunl
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Another methodological issue that can obscure and
2018-11-14

Another methodological issue that can obscure and complicate the assessment of the diet-mental health relationship relates to the covariance between health behaviours such as diet, physical activity and smoking. As these health behaviours are all associated with depression in a bidirectional manner,
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Fig displays the distribution of age
2018-11-14

Fig. 1 displays the distribution of age at onset among all twins affected with schizophrenia and schizophrenia spectrum. We observed that the age range is wider for the schizophrenia spectrum compared to schizophrenia and that spectrum disorders appear to have a slightly earlier onset than the narro
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br Acknowledgements br Data Hexahistidine tag His binding
2018-11-14

Acknowledgements Data Hexahistidine-tag (His6) binding to Nickel (Ni) chelated with nitrilotriacetic Rocilinostat (NTA) is a well-characterized process [2,3] and it is extensively used to reconstitute protein systems in giant unilamellar vesicles (GUVs) [4–6]. We made GUVs consisting of 1,2-d
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