• The gene of the sigma receptor is

  2018-11-14

  

  The gene of the sigma-1 receptor is located on chromosome 9p13, known due to its being associated with psychotic disorders [6]. The sigma-1 receptor, with its small size (223 amino-acid residue), binds with medium or high affinity to a wide range of chemical compounds of very different structural cl

• Several limitations in our study need

  2018-11-14

  

  Several limitations in our study need to be considered when interpreting its results. As mentioned above, we did not examine social capital as a construct, which is comprised of a wider range of factors than the items that were included in our study. We also are unable assert that fewer social conne

• fty720 br Materials and Methods br Results br Discussion Stu

  2018-11-14

  

  Materials and Methods Results Discussion Studies have suggested that dual-tropic strains evolve from R5 variants, and X4 viruses arise from the R5X4 strains (Pastore et al., 2004). It is unlikely that the emergence of a dual-tropic virus during the passage experiments occurred by chance bec

• In addition to classical receptor targets such as EGFR Roove

  2018-11-14

  

  In addition to ‘classical’ receptor targets such as EGFR (Roovers et al., 2007,2011; Schmitz et al., 2013; Omidfar et al., 2013), HER2 (Jamnani et al., 2012; Even-Desrumeaux et al., 2012), c-MET (Slordahl et al., 2013) and VEGFR (Behdani et al., 2012), nanobodies against new targets such as the DR5

• br Materials and Methods br Results br Discussion Although g

  2018-11-14

  

  Materials and Methods Results Discussion Although genome-wide association studies provide a systematic, powerful, and unbiased method for studying the common disease/common variant (CDCV) hypothesis of complex disorders such as schizophrenia, the identification of susceptibility loci for sc

• A number of animal models

  2018-11-14

  

  A number of animal models have been developed for studying the pathogenesis and evaluating countermeasures for ZIKV infection. Rhesus macaques with subcutaneous ZIKV inoculation develop mild clinical signs that resemble the self-limiting illness in most infected immunocompetent adults (Dudley et al.

• br T Cell specific Immunotherapies

  2018-11-14

  

  T Cell-specific Immunotherapies Have Proved Ineffective at Blocking Relapsing MS The question remains about the nature of the peripheral target for immunotherapy. There is abundant evidence to suggest that MS is a mainly CD4 Th1/Th17 T-cell mediated disease (Martin et al., 2016). This concept is

• order Cy3.5 hydrazide br propose that the absence of violet

  2018-11-14

  

  propose that the absence of “violet” light (VL, near ultraviolet (UV), below 400nm) in our industrialized world is a major contributing factor for the recent epidemic increase in myopia. They conclude from their study that artificial lighting should be revised to include a UV component, as in sunl

• Another methodological issue that can obscure and

  2018-11-14

  

  Another methodological issue that can obscure and complicate the assessment of the diet-mental health relationship relates to the covariance between health behaviours such as diet, physical activity and smoking. As these health behaviours are all associated with depression in a bidirectional manner,

• Fig displays the distribution of age

  2018-11-14

  

  Fig. 1 displays the distribution of age at onset among all twins affected with schizophrenia and schizophrenia spectrum. We observed that the age range is wider for the schizophrenia spectrum compared to schizophrenia and that spectrum disorders appear to have a slightly earlier onset than the narro

• br Acknowledgements br Data Hexahistidine tag His binding

  2018-11-14

  

  Acknowledgements Data Hexahistidine-tag (His6) binding to Nickel (Ni) chelated with nitrilotriacetic Rocilinostat (NTA) is a well-characterized process [2,3] and it is extensively used to reconstitute protein systems in giant unilamellar vesicles (GUVs) [4–6]. We made GUVs consisting of 1,2-d

• br Data Dataset provided in this

  2018-11-14

  

  Data Dataset provided in this article represent the results of PPD induction of cassava roots, cultivated in Santa Catarina state, Brazil and spectrophotometric data of enzymatic activities during cassava storage (fresh samples and those stored during 3, 5, 8 and 11 days). Differently from those

• Introduction Adolescence is a transitional period

  2018-11-14

  

  Introduction Adolescence is a transitional period beginning with the onset of puberty and culminating in the assumption of a stable adult role (Lerner and Steinberg, 2004). There is considerable individual variability in both its onset and length. While the onset of adolescence is likely to be depe

• In the reward cue AS task sensitivity

  2018-11-14

  

  In the reward cue AS task, sensitivity to reward cue was used to increase top-down or executive cognitive control in inhibiting a prepotent response (saccade). The incentive used in this study was relatively small ($10 total upon task completion), and no feedback was provided to participants on whet

• br Using the PECANS checklist Several years ago Pfeifer

  2018-11-14

  

  Using the PECANS checklist Several years ago (Pfeifer et al., 2011), one of us (JHP) examined longitudinal change in reactivity to emotional facial expressions during the transition from late childhood to early adolescence. The study took a relatively precise look at a specific Pyridoxal isonicot

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